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. 2020 Aug 28;11:959. doi: 10.3389/fneur.2020.00959

Table 3.

Summary of modeling and application in ICP signal.

References Application Features or information Modeling approach Performance or delivery
Quachtran et al. (81) IHD CNN based features Regression; CNN, CNN + Autoencoder * ACC: 92.05%
Scalzo et al. (82), Scalzo and Hu (39) IHD MOCAIP Metrics improved by CDF; Trending features Threshold-based; SR-DA, SVM, SR-KDA* AUC: 85.9%; Reduce FPR by 31%
Soehle et al. (71) IHD Complexity (scaling exponent, SampEn, multiscale entropy) Statistical analysis scaling exponent (p < 0.001), SampEn (p = 0.004), MSE (p < 0.05)
Scalzo et al. (41) IHP MOCAIP Metrics with backward sequential feature selection MLR; Adaboost; Extra-Tree*; AUC: 96%, SPE: 98%, SEN: 93% (1 min prior to the elevation)
Xiao et al. (80) IHP Optimal MOCAIP metrics found by DE algorithms Regularized quadratic discriminator SPE: 99%, SEN: 37% (5 min prior to the elevation)
Hamilton et al. (83) IHP Top 10 MOCAIP metrics found by PSO A quadratic classifier (QDC) ACC: 77%, SEN: 90%, SPE: 75% (5 min prior to the elevation)
Hornero et al. (73) IHD ApEn Statistical analysis: non-parametric bootstrap hypothesis testing p < 0.01 (IH group vs. recovering group)
Teplan et al. (50) LOP 7 Time domain features hGMMs, ROC analysis YI = 0.33, SPE: 85%, SEN: 48%
Pimentel et al. (84) LOP GPs based dynamic features, PRx-based statistical features GPs-based, PRx-based, Combined Model* ACC: 74%, SPE: 65%, SEN: 83%, AUC: 76%
Güiza et al. (54) LOE Insult Intensity (I), Insult duration (D), LAx Multivariate logistic regression models and color-coded plot ICP- time burden Visualization,
Howells et al. (8) LOE Pressure reactivity indices in various frequency band Statistical analysis: correlation, Spearman's R, two-tailed Wilcoxon matched pairs test ρ = −0.46 (correlation with GOSe)
Lazaridis et al. (85) LOE PRx, Cumulative area under the curve above threshold Logistic regression models, AUC: 0.77, 95% CI 0.70–0.83
Lu et al. (75) LOE and LOP Multiscale entropy Statistical analysis: ANOVA, Logistic regression Favorable (F = 28.7, p < 0.0001), Unfavorable (F = 17.21, p < 0.0001) ACC: 82%, SPE: 94%, SEN: 50%

IHD, Intracranial Hypertension Detection; IHP, Intracranial Hypertension Prediction; LOE, Long-term Outcome Evaluation; LOP, Long-term Outcome Prediction; ACC, Accuracy; SPE, Specificity; SEN, Sensitivity; AUC, Area Under receiver operating characteristic Curve; CNN, Convolutional Neural Networks; DE, differential evolution; hGMMs, hierarchical Gaussian mixture models; YI, Youden index; GPs, Gaussian processes; Lax, low-frequency autoregulation index; GOSe, extended Glasgow Out- come Scale; ANOVA, Analysis of Variance; ApEn, Approximate Entropy; PSO, Particle Swarm Optimization; SR-DA, Spectral regression- discriminant analysis; SR-KDA, Spectral Regression-Kernel Spectral Regression.

*

is the algorithm with best performance.