Fig. 3.

Schematic representation of selected splicing variants identified by subcloning and sequencing of ABO cDNA. ABO*A1.01 cDNA indicates the normal full‐length ABO mRNA transcript, as identified in the ABO*A.01 wild type control. The splicing variants V1 to V3 were predicted to result in frameshift mutations and truncation of the encoded transferase. The V1 and V2 cDNAs were used for transfection of HeLa cells. E1‐E7 Exons 1‐7; # Exon 5 c.236‐239del; * Intron 5 Ins 21‐55; Skipped exons are indicated by the wavy line.