Table 2.
Baseline characteristics of severe asthma cohorts
| CPRD (n, %) | SIDIAP (n, %) | IPCI (n, %) | AARHUS (n, %) | PEDIANET (n, %) | HSD (n, %) | |
|---|---|---|---|---|---|---|
| Total | 9162 | 1139 | 1858 | 1207 | 137 | 780 |
| Female | 3705 (40.4) | 481 (42.2) | 806 (43.4) | 406 (33.6) | 34 (24.8) | 292 (37.4) |
| Male | 5457 (59.6) | 658 (57.8) | 1052 (56.6) | 801 (66.4) | 103 (75.2) | 488 (62.6) |
| Age (mean, min‐max) | 11.0 (5.0‐17.9) | 8.60 (5.0‐17.9) | 13.1 (5.0‐17.9) | 10.4 (5.0‐17.9) | 9.3 (5.0‐12.9) | 14.5 (2.4) |
| Incident asthma | 436 (4.8) | 164 (14.4) | 122 (6.6) | 102 (8.5) | 6 (4.4) | 79 (10.1) |
| Prevalent asthma | 8726 (95.2) | 975 (85.6) | 1736 (93.4) | 1105 (91.5) | 131 (95.6) | 701 (89.9) |
| History of exacerbations | ||||||
| Yes | 562 (6.1) | 215 (18.9) | 49 (2.6) | 40 (1.7) | 1 (0.8) | 55 (7.1) |
| No | 8600 (93.9) | 924 (81.1) | 1809 (97.4) | 1167 (98.3) | 136 (99.3) | 725 (92.9) |
| Atopy | 4724 (51.6) | 407 (35.7) | 789 (42.5) | 194 (16.1) | 54 (39.4) | 190 (24.4) |
| GERD | 375 (4.1) | 23 (2.0) | 34 (1.8) | 14 (1.2) | 3 (2.2) | 16 (2.1) |
| Diabetes mellitus | 25 (0.3) | 2 (0.2) | 4 (0.2) | 6(0.5) | 0 | 2 (0.3) |
| Obesity | 2541 (27.7) | 522 (45.8) | 174 (9.4) | 45 (3.7) | 60 (43.8) | 57 (7.3) |
| Chronic rhinosinusitis | 475 (5.2%) | 3 (0.3%) | 12 (0.6%) | 0 | 0 | 7 (0.9%) |
| Nasal polyposis | 31 (0.3%) | 0 | 3 (0.2%) | 1 (0.1%) | 0 | 0 |
Abbreviation: GERD, gastro‐oesophageal reflux disease