Table 4.
Serotype | Ubiquitination | Phosphorylation | SUMOylation | Glycosylation | Acetylation | Total PTMs |
---|---|---|---|---|---|---|
AAV1 | – | – | – | – | – | 0 |
AAV2 | 1 | 1 | 1 | 4 | – | 7 |
AAV3 | – | 1 | – | 1 | 1 | 3 |
AAV4 | 1 | – | – | – | – | 1 |
AAV5 | 3 | 1 | 1 | 4 | – | 9 |
AAV6 | – | – | – | – | 1 | 1 |
AAV7 | – | 1 | 1 | 3 | 1 | 6 |
AAV8 | – | 1 | – | 1 | 1 | 3 |
AAV9 | 2 | 3 | 3 | 2 | 1 | 11 |
AAVrh10 | 2 | 3 | 1 | 4 | 1 | 11 |
Total no. of sites | 9 | 11 | 7 | 19 | 6 | 52 |
Abundance of PTMs in AAV | 17.30% | 21.15% | 13.46% | 36.53% | 11.53% |