Table 4.

Associations between anxiety and laboratory measures of inflammation for adolescent JIA patients (n = 136)^a

Dependent variable	β, unstandardized coefficient	P, dependent variable significance	95% CI for β, unstandardized coefficient
Log serum IL‐6, pg/ml (n = 90)	0.000	0.863	–1.505, 0.637
Log serum CRP, mg/liter (n = 87)	0.001	0.702	–0.384, 0.702
Log serum cortisol, mg/ml (n = 85)	–0.001	0.363	–0.004, 0.001
Log stimulated IL‐6, pg/ml (n = 86)	0.001	0.447	–0.002, 0.004

^aData were analyzed using multiple linear regression models. Independent variable was anxiety. Age, sex, and time of day of blood sample collection (e.g., morning, afternoon) were controlled for in all models. Serum interleukin 6 (IL‐6), serum C‐reactive protein (CRP), serum cortisol, and lipopolysaccharide‐stimulated IL‐6 were log transformed; anxiety was not log transformed. JIA = juvenile idiopathic arthritis; 95% CI = 95% confidence interval.