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. 2020 Mar 23;72(2):656–670. doi: 10.1002/hep.31052

Table 1.

Lipid Levels in Lipoproteins of LHM Receiving Hepatocytes From Different Donors

LHM‐F1 (n = 11) LHM‐F2 (n = 12) LHM‐M1 (n = 8) LHM‐M2 (n = 5) Kruskal‐Wallis Test
Total Cholesterol (mmol/L) 2.6 (0.5) 4.7 (1.0) 3.1 (0.9) 4.0 (0.6) P < 0.01
VLDL/remnants‐C (mmol/L) 0.5 (0.2) 0.4 (0.1) 0.4 (0.3) 1.5 (0.4) P < 0.01
LDL‐C (mmol/L) 1.7 (0.4) 2.9 (1.0) 2.4 (0.6) 2.4 (0.5) P < 0.01
HDL‐C (mmol/L) 0.4 (0.2) 1.4 (1.1) 0.2 (0.2) 0.3 (0.1) P < 0.01
(LDL/HDL)‐C 4 (2) 2 (2) 17 (19) 11 (5) P < 0.01
Total CE (mmol/L) 2.1 (0.6) 3.8 (0.8) 2.4 (0.7) 3.2 (0.2) P < 0.01
VLDL/remnants‐CE (mmol/L) 0.4 (0.2) 0.3 (0.1) 0.3 (0.2) 1.1 (0.3) P < 0.01
LDL‐CE (mmol/L) 1.3 (0.4) 2.3 (0.7) 1.9 (0.5) 1.9 (0.3) P < 0.01
HDL‐CE (mmol/L) 0.3 (0.1) 1.1 (0.9) 0.1 (0.2) 0.3 (0.1) P < 0.01
Total FC (mmol/L) 0.5 (0.1) 0.9 (0.2) 0.7 (0.2) 0.9 (0.4) P < 0.01
VLDL/remnants‐FC (mmol/L) 0.1 (0.0) 0.1 (0.0) 0.1 (0.1) 0.4 (0.1) P < 0.01
LDL‐FC (mmol/L) 0.3 (0.1) 0.6 (0.2) 0.5 (0.1) 0.5 (0.2) P < 0.01
HDL‐FC (mmol/L) 0.1 (0.1) 0.3 (0.2) 0.1 (0.1) 0.1 (0.0) P < 0.01
Total TG (mmol/L) 0.8 (0.2) 1.2 (0.4) 0.8 (0.4) 0.9 (0.1) P < 0.01
VLDL/remnants‐TG (mmol/L) 0.3 (0.1) 0.4 (0.2) 0.3 (0.2) 0.6 (0.0) P < 0.01
LDL‐TG (mmol/L) 0.3 (0.1) 0.7 (0.2) 0.4 (0.2) 0.3 (0.0) P < 0.01
HDL‐TG (mmol/L) 0.1 (0.1) 0.1 (0.1) 0.1 (0.0) 0.1 (0.0) P = 0.24
Total PL (mmol/L) 1.8 (0.2) 3.5 (0.6) 1.9 (0.5) 2.5 (0.8) P < 0.01
VLDL/remnants‐PL (mmol/L) 0.2 (0.1) 0.2 (0.1) 0.2 (0.2) 0.9 (0.2) P < 0.01
LDL‐PL (mmol/L) 0.8 (0.2) 1.1 (0.5) 1.0 (0.3) 1.3 (0.2) P < 0.01
HDL‐PL (mmol/L) 0.8 (0.3) 2.1 (0.7) 0.6 (0.4) 0.7 (0.2) P < 0.01

Data are presented as the median and interquartile range. Kruskal‐Wallis test followed by Dunn’s multiple comparison test showed significant differences (P < 0.01) in all lipoprotein lipids (except for HDL triglycerides).

Abbreviations: C, cholesterol; CE, cholesteryl esters; FC, free (or unesterified) cholesterol; PL, phospholipids; TG, triglycerides.