Table 1.
Characteristics of the children and their mothers
| All patients (N = 5265) | Never eczema phenotype (n = 3995) | Ever eczema phenotypea (n = 1270) | |
|---|---|---|---|
| Maternal characteristics | |||
| Age at enrolment (years), mean ± SD | 31·5 ± 4·6 | 31·5 ± 4·6 | 31·4 ± 4·6 |
| Parity, nulliparous, n (%) | 3072 (58) | 2280 (57) | 792 (62) |
| Maternal education, higher, n (%) | 3001 (57) | 2277 (57) | 724 (57) |
| Maternal psychiatric symptom scale, median (IQR) | 0·1 (0·1–0·3) | 0·1 (0·1–0·3) | 0·2 (0·1–0·3) |
| Child characteristics | |||
| Sex, female, n (%) | 2652 (50) | 2041 (51) | 611 (48) |
| Gestational age at birth (weeks), median (IQR) | 40·1 (39·0–41·0) | 40·1 (39·0–41·0) | 40·1 (39·0–41·0) |
| Birthweight (g), mean ± SD | 3446 ± 567 | 3454 ± 569 | 3422 ± 559 |
| Ethnicity, non‐European, n (%) | 1331 (25) | 984 (25) | 347 (27) |
| Breastfeeding, ever, n (%) | 4857 (92) | 3695 (93) | 1162 (92) |
| Sleep problems at 2 months, yes, n (%) | 615 (12) | 447 (11) | 168 (13) |
| Eczema phenotypes, n (%)b | |||
| Never | 3995 (76) | 3995 (100) | 0 |
| Early transient | 434 (8) | 0 | 434 (34) |
| Mid‐transient | 302 (6) | 0 | 302 (24) |
| Late transient | 412 (8) | 0 | 412 (32) |
| Persistent | 122 (2) | 0 | 122 (10) |
| Emotional and behavioural problems at age 10 years, median item score (IQR)b | |||
| Internalizing problems | 3 (1–7) | 3 (1–6) | 4 (2–7) |
| Anxious‐depressed symptoms | 1 (0–3) | 1 (0–3) | 1 (0–3) |
| Withdrawn‐depressed symptoms | 1 (0–2) | 0 (0–2) | 1 (0–2) |
| Somatic symptoms | 1 (0–2) | 1 (0–2) | 1 (0–2) |
| Externalizing problems | 2 (0–5) | 2 (0–5) | 3 (1–6) |
| Aggressive behaviour symptoms | 2 (0–4) | 1 (0–4) | 2 (0–5) |
| Attention problems | 2 (1–5) | 2 (1–5) | 3 (1–6) |
Values are presented after imputation. aEver eczema phenotype consists of early transient, mid‐transient, late transient and persistent eczema phenotypes. bData were not imputed, and were missing for ever/never eczema at age 10 years (29%), and emotional and behavioural problems at age 1·5 (12%), 3 (12%), 6 (13%) and 10 years (26%).