Table 1.

Normalized abundance ± SEM of gene products related to glycolysis and mitophagy. Treatments include a control (cultured at 5% O₂ for 3 days), CoCl₂ treatment (100 µM CoCl₂ for 24 hr), and a hypoxic treatment (cultured at 1% O₂ for 3 days)

Gene name	Control	CoCl2	Hypoxia
SLC2A1 *	1.88 ± 0.38a	3.25 ± 0.32b	2.29 ± 0.12a,b
SLC2A3 *	1.61 ± 0.26b	3.25 ± 0.39b	3.75 ± 0.34b
HK1 *	2.02 ± 0.17a	3.30 ± 0.25b	3.02 ± 0.18b
HK2 *	10.59 ± 1.92a	22.36 ± 1.68b	19.24 ± 1.03b
GAPDH *	3.27 ± 0.34a	6.38 ± 0.49b	4.33 ± 0.44b
PGK1 *	1.03 ± 0.10a	2.06 ± 0.09b	1.77 ± 0.10b
ENO1 *	5.88 ± 0.44a	10.28 ± 0.68b	9.15 ± 0.97b
PKM2 *	3.70 ± 0.25a	6.30 ± 0.59b	5.59 ± 0.48b
PDK1 *	3.82 ± 0.48a	7.10 ± 0.05b	5.66 ± 0.51c
LDHA *	2.16 ± 0.22a	3.45 ± 0.28b	3.57 ± 0.26b
LDHB	0.11 ± 0.01	0.11 ± 0.001	0.12 ± 0.02
BNIP3 *	2.02 ± 0.40a	5.54 ± 0.32b	3.69 ± 0.31c
TALDO1	0.81 ± 0.10	1.03 ± 0.09	0.85 ± 0.09
EPAS1	0.32 ± 0.07	0.55 ± 0.17	0.24 ± 0.04
YWHAG	0.39 ± 0.04	0.44 ± 0.04	0.39 ± 0.02
BCL2	0.55 ± 0.03	0.65 ± 0.07	0.53 ± 0.05

Note: ^a,b,cRepresent differences between treatments with p < .05 considered significant.

Abbreviation: SEM, standard error of mean.

^*Indicates genes that are HIF targets.