Figure 4.

Saponification and second lipase‐catalyzed acetylation of enantiomerically enriched alcohol (R)‐8 (94.0 % ee). A) Transformations of (R)‐7 (96.2 % ee). B) Amounts [%] of remaining alcohol 8 and formed acetate 7 during the reaction period. C) Development of the ee values of alcohols (R)‐8/(S)‐8 and acetate (R)‐7 during the transformation. The decreased ee value of acetate (R)‐7 at the beginning of the transformation is due to very small amounts of acetate 7 (0.04 %) in the starting material (R)‐8.