Table 1.
Characteristic of study population. Comparison between patients (n = 27) before (V0) and after 28 days of therapy (V1). Values are expressed in median (IQR). Wilcoxon test P‐value reported (*P < .05). IPSS‐QoL corresponds to IPSS question number 8. IIEF‐15 domains
| V0 (n = 27) | V1 (n = 27) | P | |
|---|---|---|---|
| Age (years) | 67 (59;70) | – | – |
| BMI (kg/m2) | 25.4 (24.7;28.9) | – | – |
| Ultrasound | |||
| PV (mL) | 44.5 (38.0;61.6) | 42.1 (33.8;61.5) | 0.039* |
| Adenome volume (mL) | 16.7 (12.0;27.3) | 14.3 (10.1;24.0) | 0.089 |
| LUTS questionnaire | |||
| IPSS | 11.0 (5.8;23.2) | 10.0 (6.0;16.0) | 0.045* |
| IPSS‐QoL | 3.0 (1.0;3.2) | 2.0 (1.0;3.) | 0.018* |
| Sexual function questionnaire (IIEF‐15) | |||
| EF | 27.0 (15.0;28.0) | 27.0 (12.0;28.0) | 0.417 |
| IS | 9.0 (7.0;12.0) | 10.0 (5.0;12.0) | 0.554 |
| SD | 7.0 (6.0;9.0) | 8.0 (6.0;8.0) | 0.551 |
| OF | 10.0 (6.0;10.0) | 10.0 (9.0;10.0) | 0.152 |
| OS | 8.0 (4.0;8.0) | 8.0 (6.0;8.0) | 0.542 |
| Hormones | |||
| FSH (mUI/mL) | 7.1 (4.2;12.2) | 6.5 (4.4;11.0) | 0.583 |
| LH (mUI/mL) | 3.4 (2.3;5.9) | 3.0 (2.1;7.1) | 0.075 |
| Testosterone (nmol/L) | 16.0 (13.0;20.3) | 15.6 (12.6;21.1) | 0.738 |
| Estradiol (pg/mL) | 23.8 (18.9;34.1) | 21.5 (17.6;25.7) | 0.073 |
| Lipid and glucose metabolism | |||
| Glycemia (mg/dL) | 97.0 (90.0;108.0) | 102.0 (94.0;113.0) | 0.989 |
| HbA1c (%) | 5.5 (5.2;6.1) | 5.7 (5.2;6.0) | 0.092 |
| Total cholesterol (mg/dL) | 183.0 (149.0;196.0) | 179.0 (155.2;208.0) | 0.109 |
| HDL (mg/dL) | 48.0 (42.0;64.0) | 49.0 (41.9;63.7) | 0.909 |
| LDL (mg/dL) | 98.0 (78.0;112.0) | 99.0 (82.7;124.2) | 0.106 |
| Triglycerides (mg/dL) | 110.0 (81.0;135.0) | 108.0 (72.0;165.5) | 0.611 |
| Kidney function | |||
| Creatinine (mg/dL) | 1.0 (0.8;1.2) | 0.9 (0.9;1.1) | 0.274 |
| Urea (mg/dL) | 36.0 (32;41.4) | 38.9 (31.9;46.7) | 0.679 |
| Inflammation markers | |||
| WBCs (×109/L) | 6.7 (5.2;8.2) | 6.3 (5.4;8.1) | 0.755 |
| Neutrophils (×109/L) | 3.7 (2.9;4.7) | 3.8 (2.9;4.5) | 0.719 |
| Lymphocytes (×109/L) | 1.9 (1.4;2.3) | 1.9 (1.4;2.2) | 0.943 |
| ESR (mm/h) | 9.0 (3.5;15.0) | 6.0 (4.0;10.0) | 0.088 |
| CRP (μg/L) | 1600 (600;2500) | 1400 (500;2025) | 0.078 |
| Fibrinogen (g/L) | 3.1 (2.6;3.3) | 2.9 (2.6;3.3) | 0.548 |
| PSA (ng/mL) | 1.9 (0.7;3.6) | – | – |
Abbreviations: EF, erectile function; IS, intercourse satisfaction; OF, orgasmic function; OS, overall satisfaction; SD, sexual desire.