Figure 20.

Enhanced phosphorylation of SK2‐S465 in TAB rats VMs is PKA‐dependent

A, representative western blot of SK2 and phosphorylated S465 (left) and plot of p‐S465 band optical density (OD) normalized to SK2 levels for Sham and TAB rats (right). Each lane represents a sample from a separate rat. ^* P = 0.005, paired Student's t test. B, representative western blot of SK2 and phosphorylated S465 (top) and plots of p‐S465 band OD normalized to SK2 levels for Sham and TAB rats under baseline conditions, or treated with ISO (^* P = 0.01, paired Student's t test), KN93 or H89 (^* P = 0.04, one‐way ANOVA with a Bonferroni post hoc test) (bottom).