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The effect of exogenously added pyruvate on the aerobic growth of the lrg-derivative strains. The strains, including S. mutans UA159 (WT, A), ΔlrgAB (lrgAB-deficient, B), SAB161 (lrgAB-overexpressing, C), and SAB163 (lytST-overexpressing, D) in BHI medium supplemented by different concentrations of exogenous pyruvate (0, 1, 10, and 40 mM). OD600 was monitored every 30 min at 37°C using the Bioscreen C lab system. The results are representative of three independent experiments.
