TABLE 1.
Cohort 1 (DMD: n = 18; HC: n = 11) | Cohort 2 (DMD: n = 22; HC: n = 12) | Cohort 3 (BMD: n = 23; HC: n = 13) | Cohort 4 (SMA: n = 29; HC: n = 20) | |
---|---|---|---|---|
Anatomical location | Upper arm | Lower leg | Lower leg | Upper leg |
Sequence parameters | ||||
First TE | 8.0 ms | 8.0 ms | 8.0 ms | 7.6 ms |
Time between echoes | 8.0 ms | 8.0 ms | 8.0 ms | 7.6 ms |
Number of echoes | 17 | 17 | 17 | 17 |
TR | 3000 ms | 3000 ms | 3000 ms | 4598 ms |
Slice thickness | 10 mm | 10 mm | 10 mm | 6 mm |
Slice gap | 20 mm | 20 mm | 20 mm | 0 mm |
Slices | 5 | 5 | 5 | 13 |
Resolution | 2.0 × 2.0 mm | 1.6 × 1.6 mm | 1.6 × 1.6 mm | 3.0 × 3.0 mm |
ΔChemical shift* | 0.1 mm | 1.1 mm | 1.1 mm | 0.9 mm |
Excitation pulse | ||||
Bandwidth | 1000 Hz | 1000 Hz | 1000 Hz | 768 Hz |
Gradient strength | 1.78 mT/m | 1.78 mT/m | 1.78 mT/m | 2.28 mT/m |
Refocusing pulse | ||||
Bandwidth | 632 Hz | 632 Hz | 632 Hz | 486 Hz |
Gradient strength | 1.80 mT/m | 1.48 mT/m | 1.48 mT/m | 1.90 mT/m |
Cohort 1 included Duchenne’s muscular dystrophy patients and healthy controls; cohort 2 included Duchenne’s muscular dystrophy patients and healthy controls; cohort 3 included Becker muscular dystrophy patients and healthy controls; and cohort 4 included spinal muscular atrophy patients and healthy controls.
Abbreviations: BMD, Becker muscular dystrophy; DMD, Duchenne’s muscular dystrophy; HC, healthy control; SMA, spinal muscular atrophy.
Chemical‐shift displacement difference in slice direction between excitation and refocusing pulse for fat.