Table 1.

Criteria for inclusion and exclusion

Inclusion criteria

Japanese adult women aged 30–54 years at the time of enrollment

Exclusion criteria

Individuals who: Regularly use cosmetology or food affecting the skin condition Have skin diseases or diseases affecting skin condition, and/or whose skin has abnormality requiring treatment Need to wear masks or to blow their nose due to allergic rhinitis, and/or may develop the allergy during the study Have chronic diseases Have serious disorders and/or past histories of serious disorders Excessively take alcohol Smoke (>20 cigarettes/day) Have history of serious drug allergy and/or serious food allergy Are pregnant/lactating, and/or desire to/likely become pregnant during the study period Are participating in other clinical trials, and/or participated in other clinical trials within 1 month Were judged to be unsuitable for enrollment based on the opinion of the principal investigator, subject background or physical findings