Figure 1.

Overlay of two ¹H‐¹³C HSQC spectra of Brd4‐BD1 selectively labeled either at positions η (green) and ϵ (red) or at position ζ (blue). For each set of spin systems, three signals are observed, which correspond to the three tryptophan residues (Trp75, Trp81 and Trp119) present in Brd4‐BD1. Note that signals for Trp81‐ζ and Trp119‐ζ (blue cross peaks) at position ¹H: 7.0 ppm/ ¹³C: 119.2 ppm, as well as Trp81‐η and Trp119‐η (green cross peaks) at position ¹H: 7.1 ppm/ ¹³C: 122.0 ppm, overlap.