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Some considerations when choosing second‐ or third‐line systemic treatment for patients with advanced HCC in clinical practice
| Second‐line treatment | Third‐line treatment | ||
|---|---|---|---|
| Sorafenib‐intolerant patients | Patients with low AFP | ||
| Regorafenib | No | Yes | No |
| Cabozantinib | Yes | Yes | Yes |
| Ramuciramab | Yes | No | No |
Abbreviations: AFP, alpha‐fetoprotein; HCC, hepatocellular carcinoma.
