Figure 2.

a) 2D (left) and 3D (right) atomic force microscopy images of DNA origami nanostructures before any incubation (top), after incubation with streptavidin (middle), and after successive incubations with streptavidin and biotinylated lysozyme (bottom) (height scale 0–3.5 nm, from darker to lighter). b) Cross‐sections of the nanostructures shown in (a) show the height change at the wells before any incubation (blue), after incubation with streptavidin (green) and after successive incubations with streptavidin and biotinylated lysozyme (red). c) Volume measurements of the particles bound to the DNA origami structures after incubation with streptavidin alone and streptavidin and biotinylated lysozyme. d) dSTORM super‐resolution microscopy images of Alexa 647 fluorophores in the DNA origami nanostructures.