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Frequent mutations in positive (green) and negative (red) regulators of the NF‐κB pathway in MM. TRAF3 is an important negative regulator and NIK an important positive regulator of the non‐canonical NF‐κB signaling pathway. Figure reproduced and adapted under the Creative Commons Attribution License (CCBY 3.0; https://creativecommons.org/licenses/by/3.0/) from Demchenko & Kuehl, Oncotarget 2010;1(1):59‐68. 2 MM, multiple myeloma; NF‐κB, nuclear factor kappa B
