Table 1.
Patient Characteristics in Insufficient Responders and Responders to Acute Treatment
| Insufficient Responders (N = 200) | Responders (N = 383) | Total (N = 583) | P Value | |
|---|---|---|---|---|
| Age (years, mean [SD]) | 39.7 (12.7) | 40.1 (13.3) | 40.0 (13.1) | .850 |
| Female, n (%) | 160 (80.0) | 287 (74.9) | 447 (76.7) | .170 |
| White/Caucasian, n (%) | 144 (72.0) | 294 (76.8) | 438 (75.1) | .279 |
| Smoking status: current or prior smoker, n (%) | 63 (32.1) | 139 (36.4) | 202 (34.9) | .311 |
| Doctor specialty, n (%)† | .011 | |||
| Primary care/Internist consultation | 131 (65.5) | 289 (75.5) | 420 (72.0) | |
| Neurologist consultation | 69 (34.5) | 94 (24.5) | 163 (28.0) | |
| Employed, n (%) | 130 (65.0) | 279 (73.0) | 409 (70.3) | .044 |
| Insurance plan, n (%) | .219 | |||
| Commercial | 137 (82.5) | 289 (87.3) | 426 (85.7) | |
| Medicare/Medicaid/Medical | 26 (15.7) | 34 (10.3) | 60 (12.1) | |
| Others | 3 (1.8) | 8 (2.4) | 11 (2.2) | |
| Migraine with aura, n (%) | 69 (34.7) | 163 (42.7) | 232 (39.9) | .062 |
| Migraine type based on headache days, n (%) | .001 | |||
| Chronic migraine (15+ headache days) | 23 (11.6) | 17 (4.5) | 40 (6.9) | |
| Episodic migraine (<15 headache days) | 176 (88.4) | 365 (95.5) | 541 (93.1) | |
| Migraine Headache Days/Month, n (%) | <.001 | |||
| 0‐3 | 102 (53.7) | 254 (69.0) | 356 (63.8) | |
| ≥4 | 88 (46.3) | 114 (31.0) | 202 (36.2) | |
| 4‐7 | 51 (26.8) | 87 (23.6) | 138 (24.7) | .406 |
| 8‐14 | 24 (12.6) | 22 (6.0) | 46 (8.2) | .007 |
| 15+ | 13 (6.8) | 5 (1.4) | 18 (3.2) | <.001 |
| Rebound headaches or medication‐overuse headaches, n (%) | 31 (15.5) | 25 (6.5) | 56 (9.6) | <.001 |
| Tension headaches, n (%) | 89 (44.5) | 141 (36.8) | 230 (39.5) | .071 |
| Family history with migraine: parent, n (%) | 88 (44.4) | 155 (40.6) | 243 (41.9) | .371 |
| Comorbidities (patient background) | ||||
| Depression | 72 (37.5) | 82 (22.0) | 154 (27.3) | <.001 |
| Anxiety | 59 (30.7) | 126 (33.8) | 185 (32.7) | .464 |
| Other psychological conditions‡ | 16 (8.3) | 14 (3.8) | 30 (5.3) | .021 |
| Neuropathic pain | 9 (4.7) | 9 (2.4) | 18 (3.2) | .145 |
All calculations were based on nonmissing values. Bold font in the P values column indicates statistically significant.
†
Consultation from which the patient was enrolled in the survey. For categorical measures, chi‐square or Fisher’s exact test was used. For continuous measures, Wilcoxon Rank‐sum test or 2‐sample t‐test was used.
‡
Other psychological conditions include panic disorder, obsessive compulsive disorder, other psychological or psychiatric symptoms except for depression and anxiety.