Table 6.
Factors Associated With Insufficient Responders to Acute Treatment vs Responders
| Factors | Odds Ratio | 95 Confidence Interval | P Value | |
|---|---|---|---|---|
| Lower Bound | Upper Bound | |||
| Ethnicity (White/Caucasian vs Other) | 0.73 | 0.45 | 1.19 | .208 |
| Living alone (Yes vs No) | 1.45 | 0.85 | 2.47 | .171 |
| Living with friend (Yes vs No) | 0.52 | 0.19 | 1.44 | .209 |
| Had depression (Yes vs No) | 1.98 | 1.21 | 3.23 | .006 |
| Had neuropathic pain (Yes vs No) | 2.01 | 0.55 | 7.29 | .289 |
| Time of administration acute treatment (When/After the pain starts vs at first sign of a migraine) | 1.83 | 1.15 | 2.92 | .011 |
| MIDAS total score | 1.04 | 1.02 | 1.05 | <.001 |
| Currently prescribed recommended acute treatments (Yes vs No) | 3.74 | 0.71 | 19.62 | .119 |
| Change in average HDPM before prescribed acute treatment (increase vs decrease) | 1.25 | 0.64 | 2.46 | .515 |
| Current most troublesome symptom: Sensitivity to light (No vs Yes) | 2.30 | 1.21 | 4.37 | .011 |
| Patient level of impairment last 6 months (Much improved vs Remained the same) | 0.59 | 0.34 | 1.05 | .072 |
| Patient level of impairment last 6 months (Slightly improved vs Remained the same) | 1.01 | 0.59 | 1.72 | .965 |
| Patient level of impairment last 6 months (Worse vs Remained the same) | 1.50 | 0.60 | 3.72 | .386 |
| Migraine Headache Days per month 15+ vs 0‐3 | 4.01 | 0.98 | 16.39 | .053 |
| Migraine Headache Days per month 4‐7 vs 0‐3 | 1.06 | 0.63 | 1.78 | .831 |
| Migraine Headache Days per month 8‐14 vs 0‐3 | 1.34 | 0.58 | 3.10 | .489 |
| Change in average HDPM before prescribed acute medication and now (no change vs decrease) | 1.75 | 1.05 | 2.90 | .031 |
The results in the table were from stepwise logistic regression with selection criteria a significance level of .3 to allow a variable into the model and a significance level of .35 for a variable to stay in the model. Odds ratio >1 with its 95% CI not including 1 indicates as a significant factor associated with acute treatment insufficient‐response while <1 with its 95% CI not including 1 is a significant factor for acute treatment response. Bold font in the P values column indicates statistically significant.
HDPM = number of headache days per month; MIDAS = Migraine Disability Assessment.