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. 2020 Jul 2;88(3):574–587. doi: 10.1002/ana.25811

TABLE 4.

Baseline CSF AB Groups

PD − A PD + A HC − A HC + A
N (% total) 281 (68.5%) 129 (31.5%) 136 (72.3%) 52 (27.7%)
Sex F (%F) 99 (35.2%) 41 (31.8%) 50 (36.8%) 18 (34.6%)
Age at CSF 61.5 (9.6) 62.2 (9.6) 60.7 (10.8) 61.0 (13.0)
Disease duration 4.2 (0.4–34.8) 4.6 (0.7–34.7) NA NA
CSF t‐tau 169.50 (85.6–467.0)

124.1 a (80.9–339.2)

Missing = 12

183.0 (93.7–420.5)

126.8b (81.96–580.8)

Missing = 3

CSF p‐tau

14.04 (8.2–40.1)

Missing = 3

10.82 a , c (8.0–32.8)

Missing = 33

15.6 (8.1–39.1)

Missing = 1

12.8 (8.2‐73.6)

Missing = 13

CSF aSyn

1522.3 (606.1–5256.9)

Missing = 1

1026.6 a (432.4–3638.3) 1696.2 (733.8–4271.3) 1131.9b (488.6–4683.1)

Data listed = frequency (%) for categorical data, mean (standard deviation) for normally distributed data or median (range) for non‐normally distributed data. Number of missing data points is noted in each cell. aSyn = cerebrospinal fluid total alpha‐synuclein; HC − A = healthy controls with normal CSF Aβ42 levels; HC + A = HC with pathologically low CSF Aβ42 levels; PD − A = Parkinson's disease with normal CSF Aβ42 levels; PD + A = PD with pathologically low CSF Aβ42 levels; p‐tau = cerebrospinal fluid phosphorylated tau at threonine 181; t‐tau = cerebrospinal fluid total tau.

a

p < 0.0001 PD + A vs PD − A;

b

p < 0.0001 HC + A vs HC − A;

c

p < 0.03 PD + A vs HC + A.