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The 293‐kb BAC clone (RP23‐40N15) containing all Hdc exons and 120 kb of 5′ and 148 kb of 3′ flanking sequence was modified by inserting GFP (green fluorescence protein) cDNA into the 1st exon. The mast cell‐ and basophil‐specific cis‐regulatory elements are located in proximity to the Hdc gene. Other myeloid lineage cell‐directed elements are located further than the 10‐kb upstream region
