Table 2.
Properties of 2 hepcidin cutoffs as a diagnostic test of iron deficiency.
| ID ferritin cutoff, ng/mL | Hepcidin cutoff, ng/mL | Sensitivity, % (95% CI) | Specificity, % (95% CI) | Positive LR (95% CI) | Negative LR (95% CI) | Correctly classified, a % |
|---|---|---|---|---|---|---|
| <15 | <10 | 93.1 (78.0–98.1) | 85.5 (80.6–89.3) | 6.4 (4.0–9.2) | 0.08 (0.02–0.27) | 86.3 |
| <15 | 96.6 (82.8–99.4) | 69.8 (63.9–75.1) | 3.2 (2.3–4.0) | 0.05 (0.01–0.27) | 72.5 | |
| <20 | <10 | 78.7 (65.1–88.0) | 88.6 (83.9–92.1) | 6.9 (4.0–11.1) | 0.24 (0.13–0.42) | 87.0 |
| <15 | 91.5 (80.1–96.6) | 73.8 (67.9–79.0) | 3.5 (2.5–4.6) | 0.12 (0.04–0.29) | 76.7 | |
| <30 | <10 | 67.6 (55.8–77.6) | 91.7 (87.2–94.7) | 8.1 (4.4–14.6) | 0.35 (0.24–0.51) | 85.9 |
| <15 | 85.3 (75.0–91.8) | 78.2 (72.3–83.2) | 3.9 (2.7–5.5) | 0.19 (0.10–0.35) | 79.9 |
a
Specific to studied population.