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. 2020 May 8;39(3):805–823. doi: 10.1007/s10555-020-09885-8

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© The Author(s) 2020

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Fig. 1 — Overview of the regulation of CAK and the role of CDK7 in regulating the cell cycle (a) and transcription (b). CAK = CDK activating kinase, CDK = cyclin-dependent kinase, CK2 = protein kinase CK2, G1 = gap phase 1, G2 = gap phase 2, M = mitosis, P = phosphate, PKCι = protein kinase C iota, Pol II = RNA polymerase II, S = synthesis, TFIIH = transcription factor II H