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. 2020 Sep 3;10:1658. doi: 10.3389/fonc.2020.01658

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Copyright © 2020 Kasimir-Bauer, Keup, Hoffmann, Hauch, Kimmig and Bittner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prevalence of primary TNBC patients with prostate cancer related transcripts detected in CTCs. (A) In 41 TNBC patients before therapy (dark blue) and 26 TNBC patients after neoadjuvant therapy (light blue) PSA, PSMA, AR-FL, and AR-V7 RNA profiles were examined. (B) Co-expression of AR-FL and AR-V7 (dark red) was detected in the majority of AR-FL+ CTCs. Some patients displayed only AR-FL+ CTCs (red), but no patient was examined to have only AR-V7+ CTCs (light red).