. 2020 Jul 21;27(10):551–559. doi: 10.1530/ERC-20-0067
This work is licensed under a Table 3.
Results of two-sample MR analysis for benign nodular thyroid disease and thyroid cancer.
| Trait | IVW | Egger | WM | PWM | |||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | Int P | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Thyroid cancer | 2.00 (1.09–3.70) | 0.039 | 1.71 (0.23–12.72) | 0.60 | 0.87 | 1.88 (1.04–3.39) | 0.037 | 1.50 (0.83–2.73) | 0.18 |
| Benign nodular thyroid disease | 4.96 (2.46–9.99) | 2.59 × 10−4 | 1.46 (0.16–13.43) | 0.74 | 0.27 | 3.84 (2.27–6.49) | 5.54 × 10−7 | 5.44 (2.90–10.21) | 1.37 × 10−7 |
Beta coefficients and P values for the inverse variant weighted (IVW), Egger, weighted median (WM) and penalised weighted median (PWM) analyses are displayed. Int P represents the P-intercept of Egger analysis, which is a measure of horizontal pleiotropy. s.e. are displayed in parentheses.