Fig. 3. Heparin-based (HP-B) hydrogel increases viability and chemoresistance. (A) The percentage of dead cells after 72 hours was significantly (*p < 0.05) higher in both control and aqueous EGF conditions compared to HP-Bhydrogels, both with and without EGF. (B) A 24-hour treatment with paclitaxel prior to the live and dead cell assay at 72 hours increased the percentage of dead cells in all the conditions. However, the difference was significantly higher (*p < 0.05, ****p < 0.0001) in both 2D conditions compared to the HP-B hydrogels. Data is represented as mean ± standard error of mean (SEM).
