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. 2020 Jul 8;70(10):1521–1532. doi: 10.1007/s12031-020-01620-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — SERINC2 expression correlates with IDH-1 status, and high expression predicts poor prognosis of IDH-1 mutation-type (mt) LGG. a, b IDH-1 wild-type (wt) LGG has high expression of SERINC2 in TCGA-LGG (a) and GSE16011 (b), but no significance was found in the GSE16011 dataset. c–h In IDH-1 mt LGG, higher SERINC2 expression showed reduced 5-year (c), 10-year (d), and 15-year (e) OS in TCGA-LGG and GSE16011. f–h dataset. **** P < 0.0001; *** P < 0.001; ** P < 0.01; * P < 0.05; ns, not significant