Table 1.

Nucleotide substitutions and amino acid changes in the Spike and Nucleocapsid proteins of 43 SARS-CoV-2 genomes from Colombia generated in this study. Sequences from other countries of South America were retrieved from GISAID database. Multiple alignment was made using the Muscle algorithm in MEGA X software. Location of the substitutions was estimated based on the reference genome NC_045512.2. Left panel: nucleotides; right panel: amino acids. The uncovered nucleotide and amino acids during complete genome sequencing are represented by an interrogate mark (?). Nucleotide and amino acid positions are indicated in the number under each gene.