Table 3.
Gene | dbSNP ID | Variation | miRNA |
|ΔΔG|
(kCal/mol) |
MirSNP | TagetScan | PolymiRTS | miRNASNP | miRdSNP | Effect |
---|---|---|---|---|---|---|---|---|---|---|
ADRA2A | rs11195419 | C/A | hsa-miR-3677-5p | 6.85 | + | + | + | Create | ||
hsa-miR-3926 | 2.2 | + | + | + | Create | |||||
hsa-miR-548s | 0.43 | + | + | + | Create | |||||
rs3750625 | C/A | hsa-miR-1207-5p | 0.05 | + | + | + | Create | |||
hsa-miR-149-3p | 1.56 | + | Enhance | |||||||
hsa-miR-2682-5p | 6.44 | + | + | Break | ||||||
hsa-miR-3150a-3p | 0.02 | + | Enhance | |||||||
hsa-miR-34a-5p | 1.38 | + | + | + | Break | |||||
hsa-miR-34b-5p | 1.5 | + | + | + | Break | |||||
hsa-miR-34c-5p | 1.56 | + | + | + | + | Break | ||||
hsa-miR-3616-3p | 0.32 | + | Decrease | |||||||
hsa-miR-4446-3p | 2.99 | + | + | + | Create | |||||
hsa-miR-449a | 0.0 | + | + | + | + | Break | ||||
hsa-miR-449b-5p | 3.29 | + | + | + | Break | |||||
hsa-miR-449c-5p | 1.11 | + | + | + | Break | |||||
hsa-miR-4514 | 0.0 | + | Enhance | |||||||
hsa-miR-4692 | 0.0 | + | Decrease | |||||||
hsa-miR-4763-3p | 0.98 | + | + | Create | ||||||
hsa-miR-512-3p | 2.74 | + | + | + | Break | |||||
hsa-miR-940 | 0.44 | + | + | + | + | Create | ||||
rs13306146 | A/G | hsa-miR-432-5p | 0.37 | + | Decrease | |||||
hsa-miR-646 | 0.16 | + | + | Break | ||||||
ASTN2 | rs7518 | C/T | hsa-miR-3189-3p | 0.3 | + | + | Break | |||
hsa-miR-5001-3p | 2.34 | + | Enhance | |||||||
hsa-miR-5089 | 0.01 | + | Break | |||||||
BDNF | rs7124442 | C/T, G | hsa-miR-142-5p | 0.65 | + | Decrease | ||||
hsa-miR-5590-3p | 0.1 | + | Enhance | |||||||
hsa-miR-922 | 0.77 | + | Break | |||||||
CHRNA4 | rs6090378 | A/G | hsa-miR-136-5p | 0.36 | + | Break | ||||
rs6011770 | C/T | hsa-miR-3186-3p | 0.23 | + | Enhance | |||||
hsa-miR-4267 | 0.04 | + | Break | |||||||
hsa-miR-4661-5p | 0.77 | + | Create | |||||||
hsa-miR-629-3p | 0.14 | + | Decrease | |||||||
CNTF | rs2515362 | T/C | hsa-miR-3174 | 0.33 | + | Enhance | ||||
hsa-miR-548ac | 0.94 | + | Break | |||||||
hsa-miR-548d-3p | 0.35 | + | Break | |||||||
hsa-miR-548h-3p | 0.9 | + | Break | |||||||
hsa-miR-548z | 0.84 | + | Break | |||||||
COMT | rs165728 | C/T, G | hsa-miR-3138 | 0.4 | + | Create | ||||
hsa-miR-4520a-3p | 1.59 | + | Create | |||||||
hsa-miR-541-3p | 1.52 | + | + | Break | ||||||
hsa-miR-654-5p | 1.76 | + | + | Break | ||||||
CPLX2 | rs3822674 | T/C | hsa-miR-4287 | 0.22 | + | Enhance | ||||
hsa-miR-4685-3p | 0.22 | + | Enhance | |||||||
hsa-miR-498 | 0.24 | + | Break | |||||||
rs1006101 | T/C | hsa-miR-3689d | 2.89 | + | + | Create | ||||
hsa-miR-4802-5p | 1.85 | + | + | Create | ||||||
hsa-miR-588 | 2.9 | + | Decrease | |||||||
hsa-miR-609 | 2.9 | + | Break | |||||||
rs4867809 | A/G | hsa-miR-4471 | 0.09 | + | + | Create | ||||
hsa-miR-892b | 0.1 | + | + | + | Create | |||||
rs1560034 | T/C | hsa-miR-4435 | 0.09 | + | Create | |||||
hsa-miR-548s | 0.39 | + | Break | |||||||
DBH | rs129882 | C/T | hsa-miR-1268a | 1.79 | + | + | Break | |||
hsa-miR-1268b | 1.68 | + | + | Break | ||||||
hsa-miR-1285-3p | 0.98 | + | + | Create | ||||||
hsa-miR-3187-5p | 1.69 | + | Create | |||||||
hsa-miR-4253 | 2.13 | + | Create | |||||||
hsa-miR-4486 | 0.35 | + | + | Break | ||||||
hsa-miR-5189 | 0.03 | + | Create | |||||||
hsa-miR-612 | 0.36 | + | + | Create | ||||||
rs1330630 | G/A, C | hsa-miR-1908 | 0.13 | + | Decrease | |||||
hsa-miR-3180 | 0.02 | + | Enhance | |||||||
hsa-miR-3180-3p | 0.07 | + | Enhance | |||||||
hsa-miR-3196 | 2.77 | + | Enhance | |||||||
hsa-miR-4697-5p | 0.01 | + | + | + | Enhance | |||||
hsa-miR-4787-5p | 0.34 | + | + | Break | ||||||
hsa-miR-609 | 0.01 | + | + | Break | ||||||
DIRAS2 | rs7854469 | T/A,C | hsa-miR-3163 | 0.07 | + | + | Decrease | |||
hsa-miR-374a-5p | 0.09 | + | + | Create | ||||||
hsa-miR-374b-5p | 0.18 | + | + | Create | ||||||
rs16906711 | C/G | hsa-miR-139-5p | 0.28 | + | + | + | Break | |||
hsa-miR-633 | 0.4 | + | Create | |||||||
rs726214 | G/A | hsa-miR-3117-3p | 2.43 | + | Create | |||||
hsa-miR-3169 | 0.1 | + | Create | |||||||
hsa-miR-3199 | 0.18 | + | + | Break | ||||||
hsa-miR-4648 | 2.29 | + | + | Break | ||||||
hsa-miR-4692 | 0.14 | + | Decrease | |||||||
DRD1 | rs686 | G/A | hsa-miR-4323 | 0.45 | + | Create | ||||
DRD2/ANNK1 | rs6278 | C/A | hsa-miR-214-3p | 1.58 | + | + | + | Break | ||
hsa-miR-298 | 1.3 | + | + | Create | ||||||
hsa-miR-3154 | 2.16 | + | + | Create | ||||||
hsa-miR-3619-5p | 1.82 | + | + | + | Break | |||||
hsa-miR-3714 | 4.48 | + | Decrease | |||||||
hsa-miR-3918 | 0.92 | + | Enhance | |||||||
hsa-miR-761 | 1.59 | + | + | + | Break | |||||
rs6279 | G/C | hsa-miR-4311 | 0.31 | + | + | Break | ||||
hsa-miR-4323 | 1.31 | + | Enhance | |||||||
hsa-miR-4758-3p | 1.85 | + | Enhance | |||||||
rs6276 | C/T | hsa-miR-1234 | 0.69 | + | + | Create | ||||
hsa-miR-3064-5p | 0.42 | + | Break | |||||||
hsa-miR-3176 | 0.03 | + | + | Break | ||||||
hsa-miR-3922-3p | 0.8 | + | + | Break | ||||||
hsa-miR-4316 | 0.68 | + | Decrease | |||||||
hsa-miR-4710 | 0.08 | + | Decrease | |||||||
hsa-miR-485-5p | 5.2 | + | Enhance | |||||||
hsa-miR-5580-5p | 0.02 | + | + | Break | ||||||
DRD5 | rs1967551 | T/C | hsa-miR-210 | 0.58 | + | Enhance | ||||
hsa-miR-4697-3p | 0.41 | + | Create | |||||||
hsa-miR-636 | 0.3 | + | Enhance | |||||||
hsa-miR-654-3p | 0.15 | + | Break | |||||||
GDNF | rs11111 | T/C | hsa-let-7f-2-3p | 2.29 | + | + | Create | |||
hsa-miR-1185-1-3p | 3.66 | + | + | Create | ||||||
hsa-miR-1185-2-3p | 3.69 | + | + | Create | ||||||
hsa-miR-3934 | 0.75 | + | Enhance | |||||||
rs3749692 | A/G | hsa-let-7a-2-3p | 0.69 | + | + | Break | ||||
hsa-let-7g-3p | 0.65 | + | + | Break | ||||||
hsa-miR-1915-3p | 0.45 | + | Enhance | |||||||
hsa-miR-3649 | 2.81 | + | Create | |||||||
hsa-miR-4700-3p | 2.22 | + | Break | |||||||
hsa-miR-5685 | 2.81 | + | Enhance | |||||||
GRIN2A | rs767749 | T/G | hsa-miR-3618 | 1.84 | + | Break | ||||
rs1420040 | A/G | hsa-miR-4645-5p | 0.37 | + | Decrease | |||||
hsa-miR-580 | 0.15 | + | Create | |||||||
rs9940680 | G/C | hsa-miR-181a-5p | 2.91 | + | Decrease | |||||
hsa-miR-181b-5p | 1.31 | + | Enhance | |||||||
hsa-miR-181d | 3.91 | + | Enhance | |||||||
hsa-miR-3663-5p | 4.64 | + | Break | |||||||
rs9933624 | T/A, C | hsa-miR-22-5p | 0.45 | + | Enhance | |||||
hsa-miR-607 | 0.71 | + | Create | |||||||
rs8045712 | C/T | hsa-miR-1343 | 0.29 | + | Decrease | |||||
rs8044472 | G/A, C | hsa-miR-4637 | 0.09 | + | Decrease | |||||
hsa-miR-4653-3p | 0.04 | + | Create | |||||||
hsa-miR-520a-5p | 0.14 | + | + | Break | ||||||
hsa-miR-525-5p | 0.13 | + | + | Break | ||||||
rs1014531 | G/A | hsa-miR-1185-5p | 1.44 | + | Enhance | |||||
hsa-miR-1266 | 1 | + | Create | |||||||
hsa-miR-197-5p | 1 | + | Create | |||||||
hsa-miR-3132 | 0.99 | + | Create | |||||||
hsa-miR-3664-3p | 1.04 | + | Break | |||||||
hsa-miR-3679-5p | 1.02 | + | Enhance | |||||||
hsa-miR-4518 | 1.87 | + | Create | |||||||
hsa-miR-510 | 1 | + | Decrease | |||||||
HTR2A | rs3125 | C/G, T | hsa-miR-3662 | 0.08 | + | Decrease | ||||
hsa-miR-3976 | 2.92 | + | + | Break | ||||||
hsa-miR-5689 | 0.2 | + | + | + | Create | |||||
HTR2C | rs1801412 | T/G | hsa-miR-10a-5p | 0.4 | + | + | Break | |||
hsa-miR-10b-5p | 2.66 | + | + | Break | ||||||
hsa-miR-141-3p | 4.61 | + | + | Create | ||||||
hsa-miR-200a-3p | 4.6 | + | + | Create | ||||||
hsa-miR-2054 | 0.86 | + | Decrease | |||||||
hsa-miR-2115-3p | 1.62 | + | Enhance | |||||||
hsa-miR-339-5p | 5.82 | + | + | Break | ||||||
MAOA | rs3027407 | A/G | hsa-miR-3120-5p | 2.49 | + | + | Create | |||
hsa-miR-4652-3p | 0.22 | + | + | + | Break | |||||
MAOB | rs3027439 | A/G | hsa-miR-3173-3p | 0.1 | + | + | Create | |||
hsa-miR-3689d | 0.2 | + | Create | |||||||
hsa-miR-4668-5p | 0.18 | + | Decrease | |||||||
hsa-miR-4668-5p | 0.18 | + | Enhance | |||||||
hsa-miR-4668-5p | 0.18 | + | Enhance | |||||||
hsa-miR-583 | 0.03 | + | Break | |||||||
rs2072745 | A/T | hsa-miR-4511 | 0.01 | + | Enhance | |||||
rs3027440 | A/G | hsa-miR-1226-5p | 0.0 | + | Decrease | |||||
hsa-miR-3616-3p | 0.02 | + | Break | |||||||
hsa-miR-4744 | 0.04 | + | Enhance | |||||||
rs17462 | T/C | hsa-miR-4299 | 0.47 | + | + | Break | ||||
hsa-miR-4738-3p | 0.84 | + | + | + | Break | |||||
hsa-miR-582-3p | 0.7 | + | + | Break | ||||||
NOS1 | rs12425729 | T/C | hsa-miR-548v | 0.97 | + | Decrease | ||||
rs10774906 | T/C | hsa-miR-4752 | 1.47 | + | Create | |||||
hsa-miR-548v | 1.46 | + | Enhance | |||||||
rs10774907 | G/A | hsa-miR-3145-3p | 0.81 | + | + | Break | ||||
hsa-miR-452-5p | 0.83 | + | Decrease | |||||||
rs9658570 | G/T | hsa-miR-3120-5p | 0.04 | + | Enhance | |||||
hsa-miR-632 | 0.05 | + | Decrease | |||||||
rs9658562 | A/T | hsa-miR-302b-5p | 1.56 | + | + | Create | ||||
hsa-miR-302c-5p | 0.35 | + | + | Create | ||||||
hsa-miR-302d-5p | 0.29 | + | + | Create | ||||||
hsa-miR-3143 | 0.17 | + | + | Create | ||||||
hsa-miR-593-5p | 0.06 | + | Enhance | |||||||
rs2682826 | G/A | hsa-miR-140-5p | 2.17 | + | Enhance | |||||
hsa-miR-29b-2-5p | 0.6 | + | Decrease | |||||||
hsa-miR-501-3p | 2.03 | + | Decrease | |||||||
hsa-miR-502-3p | 2.07 | + | Decrease | |||||||
SLC1A3 | rs1049522 | A/C | hsa-miR-3171 | 0.0 | + | + | + | Break | ||
hsa-miR-3668 | 0.0 | + | + | Create | ||||||
hsa-miR-576-3p | 0.19 | + | + | Create | ||||||
SLC6A2 | rs42879 | T/C | hsa-miR-30a-3p | 2.73 | + | Enhance | ||||
hsa-miR-30d-3p | 4.22 | + | Enhance | |||||||
hsa-miR-4263 | 1.53 | + | Break | |||||||
hsa-miR-4329 | 3.34 | + | Create | |||||||
hsa-miR-4786-5p | 0.49 | + | Create | |||||||
hsa-miR-5693 | 2.68 | + | Enhance | |||||||
rs36006 | T/C | hsa-miR-3692-3p | 0.13 | + | Break | |||||
hsa-miR-4311 | 0.12 | + | Break | |||||||
SLC6A3 | rs7732456 | A/C, T | hsa-miR-3976 | 1.86 | + | Break | ||||
hsa-miR-4427 | 1.92 | + | Decrease | |||||||
hsa-miR-5186 | 1.92 | + | Break | |||||||
hsa-miR-5585-3p | 1.51 | + | Enhance | |||||||
rs1042098 | A/G | hsa-miR-187-3p | 3.05 | + | Enhance | |||||
hsa-miR-2116-3p | 0.44 | + | Enhance | |||||||
hsa-miR-4713-5p | 2.45 | + | Enhance | |||||||
hsa-miR-5187-5p | 2.28 | + | Break | |||||||
SLC6A4 | rs7224199 | G/T | hsa-miR-1252 | 0.03 | + | Break | ||||
hsa-miR-3185 | 0.09 | + | Break | |||||||
rs3813034 | A/C | hsa-miR-2053 | 0.37 | + | Break | |||||
hsa-miR-569 | 0.42 | + | Break | |||||||
hsa-miR-571 | 0.31 | + | Decrease | |||||||
rs1042173 | A/C | hsa-miR-3163 | 0.71 | + | Enhance | |||||
hsa-miR-3942-5p | 0.1 | + | Enhance | |||||||
SLC9A9 | rs3796229 | A/G | hsa-miR-15a-3p | 0.62 | + | Decrease | ||||
hsa-miR-1972 | 0.34 | + | Enhance | |||||||
rs3796228 | T/C | hsa-miR-1260a | 5.37 | + | + | Create | ||||
hsa-miR-1260b | 0.38 | + | + | Create | ||||||
SLC18A2 | rs10377 | A/C | hsa-miR-3145-3p | 0.78 | + | Enhance | ||||
hsa-miR-3163 | 3.11 | + | Enhance | |||||||
hsa-miR-3163 | 3.11 | + | Enhance | |||||||
hsa-miR-3646 | 3.12 | + | + | Create | ||||||
hsa-miR-3662 | 3.28 | + | + | + | Create | |||||
rs14240 | T/C, A | hsa-miR-1297 | 1.98 | + | + | Break | ||||
hsa-miR-26a-5p | 2.26 | + | + | + | Break | |||||
hsa-miR-26b-5p | 2.27 | + | + | Break | ||||||
hsa-miR-3671 | 1.87 | + | + | + | Create | |||||
hsa-miR-4465 | 1.48 | + | + | Break | ||||||
hsa-miR-5002-5p | 2.32 | + | Decrease | |||||||
hsa-miR-607 | 1.8 | + | + | + | Create | |||||
rs363282 | G/A | hsa-miR-2278 | 2.64 | + | Decrease | |||||
rs363235 | T/A, C | hsa-miR-1205 | 0.97 | + | Enhance | |||||
hsa-miR-125b-2-3p | 3.2 | + | + | + | Create | |||||
hsa-miR-1297 | 0.83 | + | + | Break | ||||||
hsa-miR-26a-5p | 1 | + | + | + | Break | |||||
hsa-miR-26b-5p | 0.82 | + | + | + | Break | |||||
hsa-miR-4320 | 2.51 | + | Break | |||||||
hsa-miR-4418 | 1.35 | + | Enhance | |||||||
hsa-miR-4465 | 0.7 | + | + | Break | ||||||
hsa-miR-509-3-5p | 0.41 | + | Enhance | |||||||
hsa-miR-509-5p | 0.78 | + | Enhance | |||||||
hsa-miR-513b | 1.4 | + | Create | |||||||
hsa-miR-513c-5p | 3.87 | + | + | + | Break | |||||
hsa-miR-514b-5p | 4.36 | + | + | + | Break | |||||
rs363238 | C/A | hsa-miR-297 | 0.77 | + | Decrease | |||||
hsa-miR-3149 | 0.98 | + | + | Break | ||||||
hsa-miR-4677-5p | 0.53 | + | + | Decrease | ||||||
hsa-miR-4774-5p | 6.41 | + | + | Create | ||||||
hsa-miR-578 | 0.98 | + | + | + | Break | |||||
hsa-miR-643 | 0.98 | + | + | Break | ||||||
SNAP25 | rs3746544 | G/T | hsa-miR-3617 | 0.56 | + | Break | ||||
hsa-miR-3913-3p | 0.14 | + | Break | |||||||
hsa-miR-641 | 0.38 | + | Break | |||||||
rs1051312 | T/C | hsa-miR-3646 | 0.31 | + | Decrease | |||||
hsa-miR-3664-3p | 0.24 | + | + | Break | ||||||
hsa-miR-510 | 1.86 | + | + | Break | ||||||
rs8636 | T/A, C | hsa-miR-103b | 3.34 | + | + | + | Create | |||
hsa-miR-424-3p | 1.78 | + | + | + | Break | |||||
hsa-miR-515-5p | 0.22 | + | Enhance | |||||||
hsa-miR-519e-5p | 0.66 | + | Decrease | |||||||
SPOCK3 | rs6846930 | C/G, A | hsa-miR-495 | 0.32 | + | Break | ||||
hsa-miR-5688 | 0.33 | + | Break | |||||||
rs3762245 | A/G | hsa-miR-4260 | 0.05 | + | Decrease | |||||
hsa-miR-499b-5p | 2.59 | + | + | Break | ||||||
STX1A | rs1569061 | C/T | hsa-miR-3173-5p | 4.34 | + | Enhance | ||||
hsa-miR-661 | 0.0 | + | Enhance | |||||||
SYP | rs7889267 | G/A | hsa-miR-1266 | 0.11 | + | Decrease | ||||
hsa-miR-1321 | 0.14 | + | Create | |||||||
hsa-miR-149-3p | 0.0 | + | + | Create | ||||||
hsa-miR-3173-3p | 0.18 | + | + | Break | ||||||
hsa-miR-4270 | 0.16 | + | Create | |||||||
hsa-miR-4441 | 0.06 | + | Create | |||||||
hsa-miR-4518 | 0.1 | + | Decrease | |||||||
hsa-miR-4728-5p | 0.02 | + | Create | |||||||
hsa-miR-4739 | 2.12 | + | Create | |||||||
hsa-miR-4756-5p | 0.18 | + | Create | |||||||
hsa-miR-4779 | 0.0 | + | Break | |||||||
SYT1 | rs1245667 | T/C | hsa-miR-143-5p | 1.25 | + | + | + | + | Create | |
hsa-miR-148a-3p | 1.17 | + | + | + | + | Create | ||||
hsa-miR-148b-3p | 0.83 | + | + | + | + | Create | ||||
hsa-miR-152 | 1.35 | + | + | + | Create | |||||
hsa-miR-3189-3p | 1.85 | + | Decrease | |||||||
hsa-miR-34c-5p | 1.46 | + | + | Enhance | ||||||
hsa-miR-449a | 1.47 | + | + | Enhance | ||||||
hsa-miR-449b-5p | 1.47 | + | Enhance | |||||||
hsa-miR-4650-3p | 1.78 | + | + | Break | ||||||
hsa-miR-635 | 0.72 | + | Enhance | |||||||
hsa-miR-936 | 1.3 | + | + | + | Create | |||||
rs2248102 | G/A | hsa-miR-4327 | 3.67 | + | + | Break | ||||
VAMP2 | rs1150 | A/G | hsa-miR-5583-3p | 0.0 | + | Enhance | ||||
hsa-miR-601 | 0.0 | + | Create | |||||||
rs1061032 | T/A, C, G | hsa-miR-127-3p | 0.02 | + | Decrease | |||||
hsa-miR-149-3p | 2.7 | + | Create | |||||||
hsa-miR-4447 | 2.56 | + | + | Break | ||||||
hsa-miR-4472 | 2.12 | + | + | Break | ||||||
hsa-miR-4481 | 1.76 | + | + | Break | ||||||
hsa-miR-4728-5p | 2.47 | + | Create | |||||||
hsa-miR-4745-5p | 3.53 | + | + | Break |