Fig. 1.

Dex significantly induces liver enlargement in mice. (A) Mice were intraperitoneally treated with vehicle (corn oil, 0.1 ml/10 g) or Dex (50 mg/kg per day) for 5 days. (B) Representative morphologic pictures of mice livers of the vehicle or Dex group. (C) Liver-to-body-weight ratios. Data are expressed as mean ± S.D. (n = 5). (D) CTNNB1 staining of representative liver samples measuring the size of hepatocytes around the CV area. Scale bar, 50 μm. (E) Quantification of the size of hepatocytes around the CV area. Data are expressed as mean ± S.D. (n = 3). *P < 0.05 compared with the vehicle group.