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. 2020 Mar 3;85(9):5799–5806. doi: 10.1021/acs.joc.9b03320

Table 1. Formation of Diacid Salts from Amino Acids and Aromatic Aldehydes in Alkaline Alcohol Solutionsb.

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a

Products were washed with EtOH, dried in air and weighed. Reaction conditions: amino acid (2.0 mmol), NaOH (10 mmol, 10 M at H2O solution), aromatic aldehyde (10 mmol), 75%/25% v/v% tert-butanol/corresponding alcohol solution (4 mL); microwave vial was heated to 135 °C over 5 min and kept at 135 °C for 90 min.

b

Products emerge as an enantiomeric pair of RRR(R) and SSS(S).