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. 2020 Mar 3;85(9):5799–5806. doi: 10.1021/acs.joc.9b03320

Table 2. Formation of δ-Lactone Acids from Various Hydroxyl Diacids.

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a

Reaction conditions: Diacid (2.0 mmol), TsOH (2.0 mmol), toluene (30 mL), 24 h, reflux (Dean–Stark apparatus).

b

Diacid (1.0 mmol) and HCl (1.0 mmol) instead of TsOH.

c

As in a, but TsOH (4.0 mmol), 48 h.