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. 2020 Mar 3;38(5):1448–1453. doi: 10.1007/s10637-020-00915-4

Table 2.

Patient Characteristics (n = 14)

n (%)
Median age (range), y 65 (46–78)
Female 7 (50%)
Median prior lines of therapy (range) 5 (2–14)
Prior PI 14 (100%)
At least two prior PIs 13 (93%)
Prior IMiD 14 (100%)
Prior pomalidomide 12 (86%)
Double refractory (PI and IMiD) 14 (100%)
Prior daratumumab 6 (43%)
Prior high-dose melphalan with ASCT 11 (79%)

Fifteen patients were enrolled and 14 patients were treated. One patient was withdrawn due to neutropenia prior to VLX1570 treatment, as detailed previously

ASCT autologous stem cell transplantation, IMiD immunomodulatory imide drug, PI proteasome inhibitor