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. 2020 Mar 14;38(5):1472–1482. doi: 10.1007/s10637-020-00916-3

Table 4.

Best overall response in Caucasian and Korean patients

Patients with response, n (%) Caucasian patients Korean patients Total
BI 836826 dose BI 836826 dose
1 mg 3 mg 9 mg 25 mg 50 mg 100 mg 150 mg 200 mg Total 50 mg 100 mg Total
n = 1 n = 4 n = 3 n = 4 n = 6 n = 6 n = 6 n = 7 n = 37 n = 7 n = 4 n = 11 n = 48
ORR 0 0 0 0 0 2 (33.3) 0 0 2 (5.4) 1 (14.3) 0 1 (9.1) 3 (6.3)
CR 0 0 0 0 0 0 0 0 0 1 (14.3) 0 1 (9.1) 1 (2.1)
CRu 0 0 0 0 0 0 0 0 0 0 0 0 0
PR 0 0 0 0 0 2 (33.3) 0 0 2 (5.4) 0 0 0 2 (4.2)
SD 1 (100) 1 (25.0) 1 (33.3) 0 3 (50.0) 1 (16.7) 0 2 (28.6) 9 (24.3) 1 (14.3) 0 1 (9.1) 10 (20.8)
PD 0 2 (50) 2 (66.7) 4 (100.0) 2 (33.3) 2 (33.3) 5 (83.3) 4 (57.1) 21 (56.8) 5 (71.4) 4 (100.0) 9 (81.8) 30 (62.5)
NE 0 1 (25.0) 0 0 1 (16.7) 1 (16.7) 1 (16.7) 1 (14.3) 5 (13.5) 0 0 0 5 (10.4)

ORR overall response rate, CR complete remission, CRu complete remission unconfirmed, PR partial remission, SD stable disease, PD progressive disease, NE not evaluable