Table 4.
Patients with response, n (%) | Caucasian patients | Korean patients | Total | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BI 836826 dose | BI 836826 dose | ||||||||||||
1 mg | 3 mg | 9 mg | 25 mg | 50 mg | 100 mg | 150 mg | 200 mg | Total | 50 mg | 100 mg | Total | ||
n = 1 | n = 4 | n = 3 | n = 4 | n = 6 | n = 6 | n = 6 | n = 7 | n = 37 | n = 7 | n = 4 | n = 11 | n = 48 | |
ORR | 0 | 0 | 0 | 0 | 0 | 2 (33.3) | 0 | 0 | 2 (5.4) | 1 (14.3) | 0 | 1 (9.1) | 3 (6.3) |
CR | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (14.3) | 0 | 1 (9.1) | 1 (2.1) |
CRu | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PR | 0 | 0 | 0 | 0 | 0 | 2 (33.3) | 0 | 0 | 2 (5.4) | 0 | 0 | 0 | 2 (4.2) |
SD | 1 (100) | 1 (25.0) | 1 (33.3) | 0 | 3 (50.0) | 1 (16.7) | 0 | 2 (28.6) | 9 (24.3) | 1 (14.3) | 0 | 1 (9.1) | 10 (20.8) |
PD | 0 | 2 (50) | 2 (66.7) | 4 (100.0) | 2 (33.3) | 2 (33.3) | 5 (83.3) | 4 (57.1) | 21 (56.8) | 5 (71.4) | 4 (100.0) | 9 (81.8) | 30 (62.5) |
NE | 0 | 1 (25.0) | 0 | 0 | 1 (16.7) | 1 (16.7) | 1 (16.7) | 1 (14.3) | 5 (13.5) | 0 | 0 | 0 | 5 (10.4) |
ORR overall response rate, CR complete remission, CRu complete remission unconfirmed, PR partial remission, SD stable disease, PD progressive disease, NE not evaluable