Table 3.

Antiproliferative activity of selected compounds

Compd.	IC50 ± SD (n = 3) [µM]
	MDA-MB-231			MCF-7			MCF-10A			UMUC-3			LoVo			A549
GDC-0152	0.88 ± 0.21			[18]* ± 4			[1]*> ± 1			[13]* ± 3			[9]* ± 4			[13]* ± 4
LCL-161	0.76 ± 0.23			[19]* ± 2			[2]* ± 1			[16]* ± 5			[26]* ± 7			[11]* ± 3
13	3.39 ± 0.42			[22]* ± 6			[5]* ± 2			[6]* ± 2			[6]* ± 2			[2]* ± 1
14	2.72 ± 0.69			[20]* ± 3			[1]* ± 1			[8]* ± 3			[7]* ± 3			[5]* ± 2
41	2.58 ± 0.32			[20]* ± 7			[2]* ± 1			[5]* ± 2			[11]* ± 6			[10]* ± 3
42	2.46 ± 0.38			[16]* ± 2			[2]* ± 1			[6]* ± 3			[12]* ± 4			[23]* ± 6
CDDP	22.14 ± 5.26			5.36 ± 1.8			6.76 ± 1.2			3.73 ± 0.63			3.9 ± 1.3			1.6 ± 0.4

* - mean proliferation inhibition [%] at highest concentration used (10 µM)