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. 2020 Mar 20;38(5):1618–1626. doi: 10.1007/s10637-020-00922-5

Fig. 2.

Fig. 2

a MPTV for animals implanted with primary and secondary Renca tumors. All treatments were initiated on Study Day 1, 12 days after tumor implantation when group MPTVs = 58 mm3. IV docetaxel was administered at 10 mg/kg and 5 mg/kg on Day 1 and 11, respectively (blue diamonds). IT NanoDoce-1 (27.5 mg/kg) and IT vehicle treatments were administered on Days 1, 7, and 14 (red triangles). b Day 21 MPTV. ‡ = p < 0.0001 vs. IT vehicle; * = p < 0.001 vs. docetaxel. Error bars = ± 1 SEM