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. 2020 Jan 6;38(5):1390–1399. doi: 10.1007/s10637-019-00888-z

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© The Author(s) 2020

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Fig. 2 — Mean plasma concentration versus time profiles of free and adjusted-bound aflibercept on day 42 of cycle 1 following multiple dosing in the presence of S-1 (semi-log scale)