Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Common Terminology Criteria for Adverse Events version 5.0 grading system
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
|---|---|---|---|---|
| Bilirubin | 0–1.5 × ULN | 1.5–3.0 × ULN | 3.0–10 × ULN | > 10 × ULN |
| AST/ALT | 0–3.0 × ULN | 3.0–5.0 × ULN | 5.0–20 × ULN | > 20 × ULN |
ALT alanine aminotransferase, AST aspartate aminotransferase, ULN upper limit of normal
