Table 1.
LMWH (n = 160) |
Fondaparinux (n = 148) |
P-value | |
---|---|---|---|
Age (mean ± SD) | 65 ± 18 | 64 ± 16 | 0.84 |
Males | 87 (54.4) | 86 (58.1) | 0.91 |
Obesity (BMI ≥ 30) | 27 (16.9) | 22 (14.9) | 0.96 |
One or more risk factors for venous thrombosis⁎ | 18 (11.2) | 12 (8.1) | 0.35 |
One or more risk factors for arterial thrombosis^ | 91 (56.9) | 88 (59.5) | 0.65 |
Severe renal failure (creatinine clearance <30 ml/min)§ | 5 (3.1) | 3 (2.0) | 0.55 |
PPS° (mean ± SD) | 5.1 ± 1.4 | 4.9 ± 1.3 | 0.88 |
Baseline D-Dimer ≥2 times the cutoff value | 35 (21.9) | 32 (21.6) | 0.95 |
Values in parentheses are percentages unless otherwise indicated.
Cancer, recent trauma or surgery, hormonal treatment, already known thrombophilia, previous VTE.
Heavy smoking, diabetes, blood hypertension, hyperlipemia, symptomatic atherosclerosis.
Requiring the use of lower doses of either drug.
Padua Prediction Score (≥4 in all admitted patients) [10].