Table 1.
Age-standardized participant characteristics, at blood draw, by alcohol consumption, in the NHS/NHS2 study sample (N=1177).
| Cumulative Average Alcohol Consumption (g/day) | |||
|---|---|---|---|
| None | >0 - <5 | ≥5 | |
| Characteristic | (n=345) | (n=545) | (n=287) |
| Age at blood draw, mean (sdb)a | 54.9 (10.6) | 55.2 (9.8) | 59.2 (9.1) |
| Pack years, smokers, median (iqrb) | 0 (0, 4.0) | 0 (0, 15.0) | 7.0 (0, 22.0) |
| Alcohol, g/day, median (iqr) | 0 | 1.2 (0.6, 2.6) | 10.2 (7.4, 17.6) |
| Median tract income, $, mean (sd) | 55,947 (20,948) | 60,820 (23, 387) | 65,459 (25560) |
| BMI, kg/m2, mean (sd) | 28.0 (6.9) | 26.6 (5.6) | 24.8 (5.0) |
| Race, n(%) | |||
| Non-black | 175 (53.9) | 346 (64.9) | 236 (79.0) |
| Black | 170 (46.12) | 199 (35.1) | 51 (21.0) |
| Census region of residence, n(%) | |||
| New England | 23 (7.2) | 43 (8.4) | 22 (8.3) |
| Mid-Atlantic | 102 (30.2) | 195 (35.7) | 106 (35.7) |
| Midwest | 85 (24.2) | 128 (23.1) | 50 (18.8) |
| South | 46 (12.1) | 48 (8.5) | 28 (9.8) |
| West | 89 (26.4) | 131 (24.3) | 81 (27.4) |
| Ever oral contraceptive use, n(%) | 215 (61.2) | 383 (68.6) | 192 (70.9) |
| Menopause/Hormone use, n(%) | |||
| Pre-menopause | 128 (37.1) | 160 (29.4) | 51 (17.8) |
| Post-menopause/never | 93 (27.0) | 176 (32.3) | 86 (30.0) |
| Post-menopause/past | 36 (10.4) | 56 (10.3) | 25 (8.7) |
| Post-menopause/current | 88 (25.5) | 153 (28.1) | 125 (43.6) |
| Steroid use at blood draw, n(%) | 11 (3.3) | 22 (4.1) | 19 (6.4) |
| BLyS (pg/ml), median (iqr) | 1049.9 (843.0, 1276.3) |
1077.1 (869.8, 1315.6) |
1021.7 (832.7, 1201.5) |
| SCF (pg/ml), median (iqr) | 1083.4 (944.5, 1278.2) |
1053.9 (892.6, 1233.2) |
993.9 (855.7, 1169.8) |
| IFN-α (pg/ml), median (iqr)d | 1.7 (0.6, 2.8) |
1.6 (0.7, 3.0) |
2.0 (0.7, 3.1) |
| IP-10 (pg/ml), median (iqr)d | 59.7 (40.4, 102.0) |
58.2 (38.3, 89.6) |
59.8 (38.8, 91.4) |
| IL-10 (pg/ml), median (iqr)d | 14.1 (3.4,101.7) |
9.8 (2.1, 52.1) |
18.7 (2.8, 90.5) |
| ANA ≥ 1:40 | 70 (20.1) | 135 (24.5) | 60 (20.1) |
| ANA ≥ 1:80 | 18 (5.2) | 47 (8.6) | 15 (5.2) |
| ENAc | 12 (3.7) | 36 (6.6) | 21 (6.5) |
| dsDNA | 2 (.6) | 6 (1.1) | 2 (.6) |
a
Value is not age adjusted.
b
sd: standard deviation; iqr: inter-quartile range.
c
Anti- dsDNA, Sm, Ro/SSA, La/SSB, RNP.
d
Percent below limit of detection: 62.3% (IFN-a), 13.8% (IP-10), 71.9% (IL-10).