Supplementary Table 5.

Univariate and Multivariate Survival Analyses in Patients With Non-Cirrhotic Chronic Liver Disease and COVID-19

	Univariate model for all-cause mortality		Multivariate model for all-cause mortality (events = 62)		Multivariate model for mortality due to COVID-19 (events = 59)
	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Demographic factors
Age (per 10 year)	1.76 (1.46–2.12)	<.001	1.72 (1.40–2.12)	<.001	1.66 (1.34–2.04)	<.001
Male	1.63 (0.97–2.73)	.064
Race/ethnicity
Non-Hispanic white	1
Non-Hispanic black	0.73 (0.40–1.34)	.310
Hispanic	0.80 (0.41–1.59)	.532
Non-Hispanic Asian	1.52 (0.58–4.01)	.395
Other	0.29 (0.04–2.16)	.227
Liver-related factors
Etiology of liver disease
HCV	1
ALD	1.48 (0.62–3.55)	.376	4.72 (2.05–10.85)	<.001	7.39 (2.96–18.46)	<.001
NAFLD	0.43 (0.24–0.76)	.004
HBV	0.67 (0.23–1.99)	.472
Other	0.30 (0.07–1.31)	.110
Comorbidities
Diabetes	2.15 (1.30–3.61)	.003	1.87 (1.08–3.23)	.025
Hypertension	3.15 (1.64–6.05)	.001	2.04 (1.00–4.15)	.049	2.36 (1.14–4.91)	.021
Cardiovascular disease	2.02 (1.16–3.53)	.014
COPD	2.20 (1.15–4.22)	.018			2.01 (1.00–4.04)	.050
Behavioral factors
Smoking status
No	1
Past smoker	2.30 (1.33–3.97)	.003
Current smoker	2.43 (1.10–5.38)	.028	3.46 (1.52–7.84)	.003	2.97 (1.24–7.13)	.014
Alcohol consumption
Do not drink currently	1
Social drinking	0.43 (0.21–0.88)	.021
Current daily drinking	0.74 (0.32–1.74)	.489

NOTE. Boldface indicates statistical significance.

ALD, alcohol-related liver disease; CI, confidence interval; COPD, chronic obstructive pulmonary disease; COVID-19, coronavirus disease 2019; HBV, hepatitis B virus infection; HCC, hepatocellular carcinoma; HCV, hepatitis C virus infection; HR, hazard ratio; NAFLD, nonalcoholic fatty liver disease.