Table 4.
Results of Group Comparisons of the NBD Screening for Non-NF1 Patients (n = 271) and NF1 Patients (n = 45); Group Comparisons for Non-NF1 Patients for Tumor Location in Relation to Extent of Resection and Hydrocephalus (Adjusted P Values, *P < .05, **P < .01, ***P < .001)
| Domains | Time Points | NF1 vs Non-NF1 T1 128/21 T2 143/24 |
Non-NF1 | ||||
|---|---|---|---|---|---|---|---|
| Supratentorial Hemisphere vs Supratentorial Midline vs Infratentorial (Combined Time Points) (n = 48 vs n = 86 vs n = 137) | Infratentorial Tumor Localization Following Complete or Subtotal Resection | Infratentorial Tumor Localization for Extent of Hydrocephalus at Diagnosis | |||||
| Vermis vs Cerebellar Hemisphere T1 = 22/19 T2 = 21/24 |
Left vs Right Cerebellar Hemisphere T1 = 11/8 T2 = 13/11 |
Vermis vs Right vs Left Cerebellar Hemisphere (Combined Time Points) (n = 43 vs n = 24 vs n = 19) | No/Minor vs Moderate/ Severe T1 = 26/34 T2 = 27/24 |
||||
| Fluid intelligence (Gf) | T1 | 1.000 | 0.356 | 1.000 | 1.000 | 0.572 | 0.032* |
| T2 | 0.054 | 1.000 | 1.000 | 1.000 | |||
| Crystallized intelligence (Gc) | T1 | 1.000 | 0.032* | 1.000 | 0.637 | 0.857 | 0.322 |
| T2 | 0.208 | 1.000 | 1.000 | 1.000 | |||
| Verbal short-term memory (Gsm) | T1 | <0.001*** | 0.781 | 1.000 | 1.000 | 0.825 | 1.000 |
| T2 | 0.021* | 1.000 | 1.000 | 1.000 | |||
| Visual processing (Gv) | T1 | 0.126 | 0.794 | 1.000 | 0.496 | 0.455 | 1.000 |
| T2 | <0.001*** | 1.000 | 1.000 | 1.000 | |||
| Psychomotor speed (Gps), dominant hand | T1 | 1.000 | 0.421 | 1.000 | 1.000 | 0.456 | 1.000 |
| T2 | 0.363 | 1.000 | 1.000 | 1.000 | |||
| Psychomotor speed (Gps), nondominant hand | T1 | 1.000 | 0.027* | 0.189 | 1.000 | 0.012* | 1.000 |
| T2 | 1.000 | 0.511 | 1.000 | 1.000 | |||
| Psychomotor speed (Gps), coordination | T1 | 1.000 | 0.014* | 0.048* | 1.000 | 0.035* | 1.000 |
| T2 | 1.000 | 1.000 | 1.000 | 1.000 | |||
| Processing speed/ selective attention (Gs) | T1 | 1.000 | 0.303 | 1.000 | 1.000 | 0.093 | 1.000 |
| T2 | 0.090 | 0.224 | 1.000 | 1.000 | |||