Table 2.
Aspirin dose, mg/kg of BW1 | P-value | ||||||
---|---|---|---|---|---|---|---|
0 | 50 | 100 | 200 | SEM | Linear | Quadratic | |
Absorption rate, k2, %/h | 0.227 | 0.256 | 0.264 | 0.289 | 0.0161 | 0.02 | 0.62 |
Elimination rate, k1, %/h | 0.063 | 0.064 | 0.077 | 0.081 | 0.0082 | 0.02 | 0.67 |
MRT, h | 24.71 | 21.16 | 18.73 | 17.33 | 2.02 | 0.02 | 0.34 |
10, no aspirin; 50, 50 mg/kg of BW of aspirin; 100, 100 mg/kg of BW of aspirin; 200, 200 mg/kg of BW of aspirin.