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Multivariable Cox proportional hazards model for time to surgical intervention
| Parameter | Hazard Ratio (95% CI) | P Value |
|---|---|---|
| Age <40 years vs ≥40 years | 3.50 (1.73, 7.09) | <0.001 |
| Nodule size ≥3 cm vs <3 cm | 3.19 (1.65, 6.16) | <0.001 |
| Presence of Afirma suspicious nodule outside the index nodule, yes vs no | 16.80 (6.76, 41.73) | <0.001 |
| Compressive symptoms, yes vs no | 7.31 (3.55, 15.05) | <0.001 |
Abbreviation: CI, confidence interval.
