. Author manuscript; available in PMC: 2020 Sep 17.

Published in final edited form as: Eur J Cancer. 2017 Mar 26;77:13–20. doi: 10.1016/j.ejca.2017.02.020

Table 3.

Multivariable exact logistic regression model: SNPs within autophagy-related genes predict grade 2–3 hypertension according to genotype (discovery cohort).

SNP	n	Hypertension		Multivariable exact logistic regression^a
SNP	n	0–1	2–3	Exact odds ratio (95% CI)	P value^b
ATG13rs13448					0.017
T/T	139	118 (85%)	21 (15%)	1 (Reference)
Any C	80	77 (96%)	3 (4%)	0.23 (0.04, 0.83)
FIP200rs1129660					0.011
A/A	149	127 (85%)	22 (15%)	1 (Reference)
Any G	70	68 (97%)	2 (3%)	0.17 (0.02, 0.77)
ULK1rs9481					0.092
G/G	164	142 (87%)	22 (13%)	1 (Reference)
Any A	55	53 (96%)	2 (4%)	0.25 (0.03, 1.20)

Bold indicates statistical significant P values.

Multivariable model includes all significant SNPs in the univariate model (Table 2), adjusted for sex (female versus male), age (<65 versus ≥65) and BMI (<25 versus ≥25).

P value was based on exact conditional scores test from exact logistic regression.