Table 3.
Mean and standard deviation of dose parameters for the organs at risk.
| Structure | Metric |
TD Mean (SD) |
HT Mean (SD) |
VMAT Mean (SD) |
P‐value |
|---|---|---|---|---|---|
| CW only | |||||
| Ipsilateral lung | V20Gy | 27.0 (6.3) | 20.2 (1.2) | 19.4 (1.4) | 0.04 |
| Contralateral lung | V5Gy | 8.6 (3.6) | 8.0 (1.8) | 8.0 (3.3) | 0.01 |
| Contralateral breast | V5Gy | 2.4 (1.5) | 8.8 (1.8) | 8.5 (2.6) | <0.01 |
| D2% | 6.9 (3.6) | 7.1 (0.5) | 7.8 (1.5) | 0.27 | |
| Heart | V20Gy | 19.8 (8.7) | 14.0 (2.3) | 12.9 (1.5) | 0.06 |
| V10Gy | 41.5 (7.0) | 70.9 (6.0) | 39.8 (8.4) | <0.01 | |
| Dmean | 12.7 (2.8) | 14.2 (0.7) | 11.2 (0.9) | <0.01 | |
| LAD | Dmax | 44.6 (3.4) | 43.3 (4.5) | 44.5 (3.2) | 0.51 |
| Spinal cord | Dmax | 6.0 (4.0) | 13.0 (1.4) | 8.9 (2.9) | <0.01 |
| Esophagus | Dmax | 15.0 (20.1) | 18.8 (3.1) | 15.2 (2.4) | <0.01 |
| CW + SPC | |||||
| Ipsilateral lung | V20Gy | 37.0 (5.7) | 26.9 (1.9) | 36.7 (4.0) | <0.01 |
| V30Gy | 26.9 (5.1) | 18.3 (1.4) | 20.0 (1.6) | <0.01 | |
| Contralateral lung | V5Gy | 8.9 (3.3) | 14.8 (3.0) | 17.4 (2.3) | <0.01 |
| Contralateral breast | V5Gy | 5.9 (4.0) | 11.6 (2.5) | 8.8 (1.0) | <0.01 |
| D2% | 11.0 (8.2) | 7.4 (0.6) | 6.1 (0.2) | 0.02 | |
| Heart | V20Gy | 25.5 (8.8) | 20.5 (9.8) | 15.2 (3.6) | <0.01 |
| V10Gy | 45.7 (12.4) | 71.5 (10.8) | 60.1 (6.9) | <0.01 | |
| Dmean | 15.1 (2.0) | 15.8 (1.1) | 13.5 (1.1) | <0.01 | |
| LAD | Dmax | 45.4 (12.3) | 49.5 (1.6) | 47.0 (1.2) | <0.01 |
| Spinal cord | Dmax | 11.2 (2.1) | 25.1 (4.7) | 16.6 (0.8) | <0.01 |
| Esophagus | Dmax | 50.9 (1.4) | 50.7 (0.6) | 49.1 (0.9) | 0.02 |
| CW + SPC + AXLN | |||||
| Ipsilateral lung | V20Gy | 38.3 (4.7) | 28.1 (1.7) | 37.3 (3.5) | <0.01 |
| V30Gy | 27.8 (2.7) | 19.3 (1.0) | 20.2 (1.6) | <0.01 | |
| Contralateral lung | V5Gy | 14.9 (5.4) | 15.9 (1.6) | 15.6 (5.1) | 0.74 |
| Contralateral breast | V5Gy | 8.8 (6.4) | 12.3 (1.7) | 10.8 (5.0) | <0.01 |
| D2% | 11.3 (7.6) | 7.5 (0.6) | 6.2 (0.6) | <0.01 | |
| Heart | V20Gy | 25.7 (9.7) | 16.8 (2.7) | 15.2 (2.2) | 0.01 |
| V10Gy | 54.9 (7.0) | 75.5 (5.4) | 62.6 (5.8) | <0.01 | |
| Dmean | 15.3 (2.3) | 16.0 (0.7) | 13.6 (1.0) | <0.01 | |
| LAD | Dmax | 47.9 (2.9) | 50.1(1.5) | 45.1 (4.6) | <0.01 |
| Spinal cord | Dmax | 9.8 (2.3) | 21.7 (2.8) | 15.7 (1.0) | <0.01 |
| Esophagus | Dmax | 49.3 (2.7) | 50.0 (1.3) | 47.4 (3.3) | <0.01 |
Abbreviations: AXLN, axillary nodes; CI, conformity index; CW, chest wall; HI, homogeneity index; HT, TomoHelical; LAD, left anterior descending artery; SPC, supraclavicular lymph nodes; TD, TomoDirect; VMAT, volumetric modulated arc therapy.