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. 2020 Sep 17;15(9):e0239185. doi: 10.1371/journal.pone.0239185

Table 3. Associations between sleep quality, sleep duration, and uric acid levels based on the linear regression model.

Variables Univariate Multivariate
β 95% CI p-value β 95% CI p-value
PSQI scale
    ≥ 5 vs < 5 −0.096 −0.187 ~ −0.005 0.038 −0.085 −0.161 ~ −0.008 0.030
sleep duration
    < 7 h vs 7–9 h 0.055 −0.035 ~ 0.145 0.231 0.106 0.031 ~ 0.181 0.006
    ≥ 9 h vs 7–9 h −0.029 −0.388 ~ 0.330 0.874 0.164 −0.107 ~ 0.436 0.236
Age, years −0.009 −0.012 ~ −0.006 <0.001
Sex, male vs female 1.401 1.321 ~ 1.480 <0.001
Obesity, yes vs no 0.518 0.423 ~ 0.614 <0.001
Hypertension, yes vs no 0.227 0.103 ~ 0.351 <0.001
Diabetes mellitus, yes vs no −0.270 −0.042 ~ −0.125 <0.001
TC/HDL ratio 0.235 0.205 ~ 0.264 <0.001
eGFR <60 yes vs no −0.889 −1.021 ~ −0.756 <0.001
WBC count, 10^3/μL 0.035 0.022 ~ 0.049 <0.001
Current alcohol use, yes vs no 0.216 0.120 ~ 0.313 <0.001
Current smoking, yes vs no −0.141 −0.241 ~ −0.042 0.005
Exercise habit, yes vs no −0.005 −0.099 ~ 0.109 0.922

Interaction between sleep duration and sex, p = 0.157

Interaction between sleep quality and sex, p = 0.364

Interaction between sleep duration and sleep quality, p = 0.153

CI: confidence interval, PSQI: Pittsburgh Sleep Quality Index, BMI: body mass index, TC: total cholesterol, HDL-C, high-density lipoprotein-cholesterol, eGFR: estimated glomerular filtration rate