Table 1. Serum cytokine and chemokine levels in T/I, TIA, and control T/Ihet micea.
| T/I mice (n = 28) | TIA mice (n = 17) | Control T/Ihet mice (n = 13) | |
|---|---|---|---|
| Eotaxin | 918 (471–1607) | 928 (559–1388) | 954 (412–1760) |
| GM-CSF | 16 (8–30) | 16 (8–37) | 4 (2–38)b,c |
| IFN-γ | 38 (4–524) | 43 (2–236) | 4 (2–11) b,c |
| IL1α | 112 (28–1883) | 157 (23–1683)* | 192 (5–1605) b,c |
| IL1β | 2 (2–12) | 2 (2–265)* | 4 (1–10) |
| IL2 | 5 (2–8) | 2 (2–9) | 6 (2–11) |
| IL3 | 2 (2–4) | 2 (2–8) | 2 (2–22) |
| IL4 | 2 (2–11) | 2 (2–42) | 2 (2–2) |
| IL5 | 2 (2–11) | 2 (2–79) | 12 (2–30) b,c |
| IL6 | 19 (2–44) | 36 (4–104) | 2 (2–8) b,c |
| IL7 | 2 (2–84) | 2 (2–26) | 2 (2–14) |
| IL9 | 47 (10–487) | 69 (10–245) | 46 (46–106) |
| IL12p40 | 12 (2–98) | 7 (2–14)* | 9 (2–30) |
| IL12p70 | 4 (1–156) | 8 (1–211) | 8 (7–45) b |
| IL13 | 154 (9–350) | 186 (69–913) | 91 (58–206) |
| IL15 | 29 (8–1378) | 27 (8–1909) | 54 (22–135) |
| IL17 | 26 (4–159) | 60 (7–146) | 2 (2–7) b,c |
| LIF | 2 (2–16) | 2 (2–17) | 2 (2–2) |
| LIX | 4634 (2397–7787) | 3900 (809–7336) | 5930 (544–7824) |
| IP10 | 292 (120–670) | 355 (150–916) | 140 (27–334) b,c |
| KC | 175 (44–765) | 189 (16–1226) | 122 (68–211) |
| MCP1 | 29 (9–58) | 27 (9–479) | 46 (24–60) b |
| MIP1α | 31 (10–62) | 29 (10–258) | 24 (1–33) b |
| MIP1β | 9 (9–28) | 9 (9–22) | 36 (9–45) b,c |
| M-CSF | 20 (7–517) | 11 (6–44)* | 12 (6–33) |
| MIP2 | 80 (20–606) | 77 (37–126) | 87 (32–132) |
| MIG | 302 (68–2448) | 368 (51–907) | 49 (30–138) b,c |
| RANTES | 36 (8–328) | 21 (6–84)* | 29 (16–65) |
a Values shown represent the median (range) of cytokine/chemokine in pg/ml in cohorts of 8–10 week old mice.
b Indicates p < 0.05 for comparison of control T/Ihet versus T/I mice.
c Indicates p < 0.05 for comparison of control T/Ihet versus TIA mice.
* Indicates p < 0.05 for comparison of T/I versus TIA mice.