Fig 5.

A) Infection with more than one transmitted/founder variant was associated with lower frequencies of CD4 TEM (Terminal Effector CD4⁺ T cells), CD4 TTM (Transitional CD4⁺ T cells), higher frequencies of exhausted CD4 TCM (PD1+ Central Memory CD4+ T cells) and TLM (Tissue like memory) B cells at 0–3 months after infection. B) At 6–9 months after infection, there were higher frequencies of CD4 TTM (Transitional CD4⁺ T cells), but increased frequency of plasmablasts and CD86 expressing memory B cells.